Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395771 | 1.00 | CTSB (0.47) | CTSBCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL29182096 | 0.88 | MTNR1A (0.47) | CTSBCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL6575223 | 0.88 | CTSS (0.46) | CTSBCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL6445274 | 0.86 | CTSS (0.60) | CTSBCTSSCTSK | |
| SCHEMBL266022 | 0.85 | CTSK (0.51) | CTSBCTSSCTSKKDM4ASYK | |
| SCHEMBL118384 | 0.85 | CTSK (0.51) | CTSBCTSSCTSKKDM4ASYK | |
| SCHEMBL266021 | 0.85 | CTSK (0.51) | CTSBCTSSCTSKKDM4ASYK | |
| SCHEMBL6165666 | 0.85 | CTSS (0.44) | CTSBCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL9525653 | 0.85 | CYP2D6 (0.58) | CTSBCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL6239859 | 0.84 | MEN1 (0.46) | CTSBCTSSCTSKGABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | AUBURN UNIVERSITY (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | NQO1, NQO2, SQOR | CTSB 3350/4885CTSS 3244/4885CTSK 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.