Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MDM4 | O15151 | 2/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445765 | 0.94 | TDP1 (0.59) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL4233761 | 0.87 | TDP1 (0.77) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL6445769 | 0.83 | TDP1 (0.58) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL34933 | 0.81 | TDP1 (0.72) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL28896841 | 0.76 | TDP1 (1.00) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL1023209 | 0.74 | MAPT (0.83) | TDP1MAPTTP53MDM4MDM2 | |
| SCHEMBL3785470 | 0.73 | LMNA (0.66) | MAPTTP53MDM4ALDH1A1L3MBTL1 | |
| SCHEMBL10614008 | 0.73 | KMT2A (0.68) | TDP1MAPTTP53MDM4NPC1 | |
| SCHEMBL1110180 | 0.73 | MDM4 (0.73) | TDP1MAPTTP53MDM4NPC1 | |
| SCHEMBL28189189 | 0.73 | KMT2A (0.76) | TDP1MAPTTP53MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2483 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552120-B2 | Grafted and functionalized high 1,4-trans polybutadiene with aromatic organosulfur compound | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2013-10-08 | — | — | US | claimed |
| US-8198378-B2 | Aromatic organosulfur functionalized 1,4-cis polybutadiene | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-12 | — | — | US | claimed |
| US-20110136956-A1 | 1,4-CIS-POLYBUTADIENE FUNCTIONALIZED WITH ORGANOSULFUR COMPOUND FOR PREPARATION OF GOLF BALL CORE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2011-06-09 | — | — | US | claimed |
| US-20100081770-A1 | GRAFTED AND FUNCTIONALIZED HIGH 1,4-TRANS POLYBUTADIENE WITH AROMATIC ORGANOSULFUR COMPOUND | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2010-04-01 | — | — | US | claimed |
| US-20090156751-A1 | Aromatic Organosulfur Functionalized 1,4-cis Polybutadiene | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2009-06-18 | — | — | US | claimed |
| US-12043735-B2 | Resin modified oil extended rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-07-23 | — | — | US | disclosed |
| US-12037437-B2 | Rubber composition comprising a block-copolymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240228756-A1 | RUBBER TIRE COMPOUND CONTAINING IPN-PROMOTING RESIN | THE GOODYEAR TIRE & RUBBER COMPANY | 2024-07-11 | — | — | US | disclosed |
| US-20240209188-A1 | SYNTHETIC POLYISOPRENE AND METHOD OF SYNTHESIZING POLYISOPRENE | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LU) | 2024-06-27 | — | — | US | disclosed |
| US-12018154-B2 | Rubber composition offering high stiffness and low hysteresis | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240199862-A1 | SUSTAINABLE TIRE PRODUCED WITH HIGH RECYCLED/RENEWABLE RAW MATERIAL CONTENT | THE GOODYEAR TIRE & RUBBER COMPANY | 2024-06-20 | — | — | US | disclosed |
| US-20240199859-A1 | RUBBER COMPOSITION FOR TIRE TREAD | THE GOODYEAR TIRE & RUBBER COMPANY | 2024-06-20 | — | — | US | disclosed |
| EP-0589291-A1 | Tire with apex rubber blend | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5284195-A | Cap/base construction; base comprised of trans 1,4-polyisoprene and at least one other diene rubber; improved rolling resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0560182-A1 | Tire with tread base rubber blend | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0538723-A1 | Tire with dual cap tread | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0538700-A1 | Tire with rubber sidewall | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5174838-A | Shaping, curing an uncured pneumatic tire; isoprene, butadiene homo- and copolymers with styrene | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0505904-A1 | Tire with tread base rubber blend | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| US-4833191-A | ARAMID FIBERS IN RUBBER TO: MAKE POURABLE MIXTURE | WYROUGH & LOSER (US) | 1989-05-23 | — | — | US | disclosed |