SCHEMBL644579

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL643251	0.94	CHRM1 (0.41)	CHRM1MEN1KMT2ACHRM2CHRM4
	SCHEMBL644867	0.93	TACR2 (0.36)	CHRM1NPC1CHRM2CHRM4KDM4E
	SCHEMBL644812	0.89	L3MBTL1 (0.43)	MEN1KMT2AKDM4EALDH1A1HPGD
	SCHEMBL644808	0.86	LMNA (0.39)	CHRM1MEN1KMT2ANPC1RAB9A
	SCHEMBL645035	0.85	OPRL1 (0.37)	CHRM1NPC1CHRM4ALDH1A1LMNA
	SCHEMBL644580	0.85	KMT2A (0.42)	CHRM1MEN1KMT2ANPC1RAB9A
	SCHEMBL644211	0.83	L3MBTL1 (0.45)	MEN1KMT2AALDH1A1POLB
	SCHEMBL642944	0.82	CXCR3 (0.42)	CHRM1MEN1KMT2ANPC1RAB9A
	SCHEMBL644135	0.82	L3MBTL1 (0.42)	MEN1KMT2AALDH1A1HPGD
	SCHEMBL643063	0.78	CXCR3 (0.42)	CHRM1MEN1KMT2ACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.