SCHEMBL564584

SCHEMBL564584

Cc1ccc(-c2[c]ccc(C(C)C)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.34
TRPA1 O75762 2/20 0.33
PTGS1 P23219 1/20 0.33
CACNA1C Q13936 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
PKM P14618 1/20 0.32
MAPT P10636 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MITF O75030 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
NR2F2 P24468 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6494848 0.89 LMNA (0.36) LMNATRPA1PTGS1CACNA1CMAPT
SCHEMBL9599913 0.84 THRB (0.36) KDM4EALDH1A1RAB9ASMN1; SMN2
SCHEMBL1369636 0.83 RXRA (0.38) LMNAMAPTRXRARXRBRXRG
SCHEMBL15067062 0.82 LMNA (0.38) LMNATRPA1PTGS1CACNA1CMAPT
SCHEMBL5868259 0.81 TSHR (0.34) ALDH1A1RAB9ASMN1; SMN2
SCHEMBL4951261 0.81 KIF11 (0.35) LMNAMITFALDH1A1HTTRAB9A
SCHEMBL2724725 0.78 NPC1 (0.35) MAPTRAB9A
SCHEMBL5887096 0.78 LMNA (0.34) LMNATRPA1PTGS1CACNA1CHPGD
SCHEMBL102139 0.78 TDP1 (0.36) LMNATRPA1PKMKDM4EMITF
SCHEMBL9753779 0.78 RXRA (0.44) MAPTRXRARXRBRXRGKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729166-B2 Polymer composition for microelectronic assembly PROMERUS, LLC (US) 2014-05-20 US disclosed
US-20140024750-A1 Polymer Composition for Microelectronic Assembly PROMERUS, LLC (US) 2014-01-23 US disclosed
US-8575248-B2 Polymer composition for microelectronic assembly PROMERUS, LLC (US) 2013-11-05 US disclosed
US-20120034387-A1 Polymer Composition for Microelectronic Assembly PROMERUS LLC (US) 2012-02-09 US disclosed
US-20080050637-A1 Microfabricated Fuel Cell GEORGIA TECH RESEARCH CORPORATION (US) 2008-02-28 US disclosed