SCHEMBL6447900

SCHEMBL6447900

COC(OC)(OCC1CC1C(=O)OC(C)(C)C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
RECQL P46063 1/20 0.34
CES1 P23141 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FFAR4 Q5NUL3 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
KCNN4 O15554 1/20 0.33
KCNA3 P22001 1/20 0.32
ABCB1 P08183 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6450271 0.88 CYP1A2 (0.43) CYP2C19KMT2AKCNN4CYP3A4CYP1A2
SCHEMBL6407546 0.85 CYP2C19 (0.38) CYP2C19HIF1AKMT2AL3MBTL1FFAR4
SCHEMBL6430592 0.85 FFAR4 (0.45) CES1FFAR4CA12CA1
SCHEMBL6447636 0.85 CA1 (0.45) CA12CA1TSHR
SCHEMBL6412728 0.81 SLC6A11 (0.44) KMT2ACYP3A4CYP1A2
SCHEMBL6414764 0.81 SLC6A11 (0.44) KMT2ACYP3A4CYP1A2
SCHEMBL6530709 0.81 CHRM3 (0.43) CYP2C19CYP2D6CHRM2CHRM4CHRM5
SCHEMBL6532658 0.76 SLC6A11 (0.40) RECQLKMT2AL3MBTL1CYP3A4CYP1A2
SCHEMBL6409534 0.75 L3MBTL1 (0.43) KMT2AL3MBTL1FFAR4
SCHEMBL28940568 0.75 L3MBTL1 (0.43) KMT2AL3MBTL1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 CYP2C19 160/4885HIF1A 949/4885RECQL 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.