Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.54 |
| ▸ | HTR2A | P28223 | 9/20 | 0.54 |
| ▸ | HTR2C | P28335 | 9/20 | 0.54 |
| ▸ | HTR2B | P41595 | 9/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971438 | 0.81 | NPSR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL29439422 | 0.81 | SIGMAR1 (0.53) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL3054003 | 0.81 | SIGMAR1 (0.57) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL29447988 | 0.81 | SIGMAR1 (0.57) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL4461844 | 0.81 | SIGMAR1 (0.53) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL14358027 | 0.79 | SIGMAR1 (0.56) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL28750475 | 0.78 | SIGMAR1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL8000122 | 0.78 | SIGMAR1 (0.54) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL29683795 | 0.78 | SIGMAR1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL29683505 | 0.78 | SIGMAR1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021060276-A1 | FLUORINATING AGENT AND METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUNDS | ＡＧＣ株式会社 | 2021-04-01 | — | — | WO | disclosed |
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| WO-2014068341-A2 | CHIRAL FLUORINATING REAGENTS | ISIS INNOVATION LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |
| US-20050075501-A1 | Ammonium compounds bearing and electrophilic fluorine, reagent containing same, method using same and synthesis method for obtaining them | RHODIA CHIMIE (FR) | 2005-04-07 | — | — | US | disclosed |
| EP-1284975-B1 | AMMONIUM COMPOUNDS BEARING AN ELECTROPHILIC FLUORINE, REAGENT CONTAINING SAME, METHOD USING SAME AND SYNTHESIS METHOD FOR OBTAINING THEM | RHODIA CHIMIE SA (FR) | 2004-08-18 | — | — | EP | disclosed |
| EP-1284975-A1 | AMMONIUM COMPOUNDS BEARING AN ELECTROPHILIC FLUORINE, REAGENT CONTAINING SAME, METHOD USING SAME AND SYNTHESIS METHOD FOR OBTAINING THEM | RHODIA CHIMIE (FR) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001090107-A1 | AMMONIUM COMPOUNDS BEARING AN ELECTROPHILIC FLUORINE, REAGENT CONTAINING SAME, METHOD USING SAME AND SYNTHESIS METHOD FOR OBTAINING THEM | RHODIA CHIMIE (FR) | 2001-11-29 | — | — | WO | disclosed |
| US-5478964-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1995-12-26 | — | — | US | disclosed |
| US-5254732-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1993-10-19 | — | — | US | disclosed |
| US-5003074-A | N-fluorinated sulfonamides | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0311086-A1 | N-fluorinated sulfon amides, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1989-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | TIAM1, AFF2, AFF1 | SIGMAR1 158/4885HTR2A 1951/4885HTR2C 724/4885 |
| US-20050075501-A1 | Ammonium compounds bearing and electrophilic fluorine, reagent containing same, method using same and synthesis method for obtaining them | ARF5, AFF2, ARFGEF1 | SIGMAR1 1897/4885HTR2A 4258/4885HTR2C 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.