Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SPR | P35270 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MARS1 | P56192 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590949 | 0.80 | MARS1 (0.47) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL6452624 | 0.79 | KMT2A (0.40) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL18134658 | 0.79 | NPC1 (0.63) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL9515499 | 0.79 | NPC1 (0.63) | ALDH1A1HPGDHSD17B10KMT2ALMNA | |
| SCHEMBL731856 | 0.79 | MEN1 (0.50) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL31199123 | 0.79 | MEN1 (0.50) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL6452314 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10LMNA | |
| SCHEMBL6448933 | 0.76 | BCHE (0.46) | ALDH1A1HPGDALOX15HSD17B10KDM5A | |
| SCHEMBL3461571 | 0.75 | MAPT (0.56) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL6343068 | 0.72 | CYP1A2 (0.59) | ALDH1A1HPGDALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | ALDH1A1 287/4885HPGD 258/4885ALOX15 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.