Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16301172 | 0.83 | NPC1 (0.67) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL12002409 | 0.81 | NPC1 (0.63) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL29479317 | 0.81 | RAB9A (0.63) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL6448862 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL10645870 | 0.78 | NPC1 (1.00) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL200831 | 0.77 | MAPK1 (0.63) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL6449791 | 0.75 | LMNA (0.56) | ALDH1A1HPGDMAPTKDM4EKDM4A | |
| SCHEMBL1310395 | 0.75 | NPC1 (0.59) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL19192578 | 0.75 | NPC1 (0.73) | NPC1RAB9AFCGR1AALDH1A1HPGD | |
| SCHEMBL14124483 | 0.75 | PTGS1 (0.62) | NPC1RAB9AFCGR1AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273418-B1 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MFG CO LTD (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-4803193-A | COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0273418-A2 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |