Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | L1CAM | P32004 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ARG1 | P05089 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77381 | 0.83 | CA1 (0.77) | NPC1RAB9AKDM4EALDH1A1CYP2D6 | |
| SCHEMBL6449818 | 0.81 | RAB9A (0.61) | POLBNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL6450626 | 0.81 | POLB (0.59) | POLBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4218154 | 0.78 | CA1 (0.65) | NPC1RAB9AKDM4EALDH1A1CYP2D6 | |
| SCHEMBL14259807 | 0.78 | NPC1 (0.59) | POLBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6453963 | 0.78 | LMNA (0.65) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8373805 | 0.77 | POLB (1.00) | POLBRAB9AKDM4EALDH1A1HTT | |
| SCHEMBL6636585 | 0.76 | CA1 (0.79) | NPC1RAB9AKDM4EALDH1A1CYP2D6 | |
| SCHEMBL8374563 | 0.75 | POLB (0.70) | POLBRAB9AKDM4EALDH1A1HTT | |
| SCHEMBL6526653 | 0.74 | HTT (0.54) | POLBKDM4EALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | POLB 2806/4885NPC1 59/4885RAB9A 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.