Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648592 | 0.84 | HSP90AA1 (0.46) | P2RX7KCNH2PGRALDH1A1KMT2A | |
| SCHEMBL27542850 | 0.80 | P2RX7 (0.60) | P2RX7KCNH2ALDH1A1KMT2AMAPT | |
| SCHEMBL6650106 | 0.78 | P2RX7 (0.46) | P2RX7KCNH2ALDH1A1KMT2AMAPT | |
| SCHEMBL27164556 | 0.76 | CYP19A1 (0.44) | PGRALDH1A1KMT2AMAPT | |
| SCHEMBL6651166 | 0.74 | KDM4E (0.38) | P2RX7KCNH2TAAR1ALDH1A1 | |
| SCHEMBL7757122 | 0.74 | KDM5A (0.43) | KCNH2ALDH1A1KMT2A | |
| SCHEMBL10791418 | 0.71 | MEN1 (0.41) | KCNH2TAAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6647704 | 0.71 | P2RX7 (0.51) | P2RX7KCNH2ALDH1A1KMT2AMEN1 | |
| SCHEMBL16598261 | 0.70 | HRH3 (0.44) | KCNH2TAAR1ALDH1A1MAPT | |
| SCHEMBL20897192 | 0.70 | SIGMAR1 (0.50) | P2RX7ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222135-A1 | Active substance combination | LABORATIONS DEL DR. ESTEVE S.A. (ES) | 2005-10-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222135-A1 | Active substance combination | OPRM1, OPRK1, OPRL1 | P2RX7 528/4885KCNH2 4317/4885PGR 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.