Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.45 |
| ▸ | CTSL | P07711 | 5/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIF5B | P33176 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431484 | 0.85 | KDR (0.41) | EGFRKDRRETKIF5BRIPK2 | |
| SCHEMBL6430701 | 0.82 | EGFR (0.58) | CTSVCTSLEGFRKDRRET | |
| Hydrochloric Acid SCHEMBL6434111 | 0.81 | EGFR (0.57) | CTSVCTSLEGFRKDRRET | |
| SCHEMBL6436593 | 0.79 | MEN1 (0.43) | CTSVCTSLEGFRKDRMEN1 | |
| SCHEMBL6431005 | 0.79 | FLT1 (0.51) | CTSVCTSLPTK6EGFRKDR | |
| SCHEMBL6435558 | 0.71 | EGFR (0.41) | EGFRKDRRETKIF5BRIPK2 | |
| SCHEMBL6434993 | 0.71 | FLT1 (0.51) | EGFRKDRRETMEN1MAPT | |
| SCHEMBL7864670 | 0.71 | KDR (0.80) | EGFRKDRRETKIF5BRIPK2 | |
| SCHEMBL6434027 | 0.70 | EGFR (0.72) | EGFRKDRRETKIF5BRIPK2 | |
| SCHEMBL6430845 | 0.70 | FLT1 (0.55) | KDRRETKIF5BMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929526-B1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ASTRAZENECA AB (SE) | 2005-07-27 | — | — | EP | claimed |