Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535809 | 0.78 | PKM (0.39) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL6450214 | 0.77 | PKM (0.38) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10659189 | 0.72 | MAPT (0.40) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10674150 | 0.69 | ALDH1A1 (0.39) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10522944 | 0.68 | GABRB3 (0.41) | PKMALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL10669661 | 0.68 | LMNA (0.40) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10562676 | 0.67 | ALDH1A1 (0.35) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10388219 | 0.67 | PKM (0.38) | PKMSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL10371785 | 0.67 | MAPT (0.39) | PKMSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9587691 | 0.66 | ALDH1A1 (0.38) | PKMSMN1; SMN2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050192182-A1 | Herbicidal mixtures based on substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192182-A1 | Herbicidal mixtures based on substituted aryl ketones | DDT, CBR3, CYP1B1 | PKM 133/4885SMN1; SMN2 3929/4885ALDH1A1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.