Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762000 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL4552449 | 0.79 | RAB9A (0.40) | — | |
| SCHEMBL4555150 | 0.78 | RAB9A (0.42) | — | |
| SCHEMBL5185734 | 0.76 | PDE7A (0.39) | — | |
| SCHEMBL5176743 | 0.76 | PDE4B (0.39) | — | |
| SCHEMBL5963533 | 0.75 | POLB (0.36) | KHK | |
| SCHEMBL4554789 | 0.68 | ALDH1A1 (0.49) | — | |
| SCHEMBL6437921 | 0.65 | PDE4B (0.40) | — | |
| SCHEMBL3422561 | 0.64 | LMNA (0.38) | — | |
| SCHEMBL6469770 | 0.63 | KAT2B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539753-A2 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-15 | — | — | EP | claimed |
| WO-2004024728-A2 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-03-25 | — | — | WO | claimed |