SCHEMBL6450347

SCHEMBL6450347

CCCCC(Cl)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.36
ALDH1A1 P00352 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
CA2 P00918 2/20 0.31
CA1 P00915 1/20 0.31
TSHR P16473 4/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP3A4 P08684 1/20 0.31
FDPS P14324 1/20 0.31
HSD17B10 Q99714 1/20 0.30
LMNA P02545 1/20 0.30
FAAH O00519 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7856018 0.90 LMNA (0.39) DNM1ALDH1A1TSHRFDPSHSD17B10
SCHEMBL1245648 0.83
SCHEMBL27574896 0.82 DNM1 (0.35) DNM1ALDH1A1TDP1CA2CA1
SCHEMBL28136609 0.76 DNM1 (0.38) DNM1ALDH1A1TDP1CA2CA1
SCHEMBL8465036 0.76 DNM1 (0.38) DNM1ALDH1A1TDP1CA2CA1
SCHEMBL8310868 0.74 DNM1 (0.36) DNM1ALDH1A1TDP1CA2CA1
SCHEMBL16969615 0.74 FDPS (0.38) DNM1ALDH1A1TDP1CA2CA1
SCHEMBL1961203 0.73 LMNA (0.38) DNM1ALDH1A1TSHRFDPSLMNA
SCHEMBL28332620 0.73 LMNA (0.38) DNM1ALDH1A1TSHRFDPSLMNA
SCHEMBL27326152 0.73 LMNA (0.38) DNM1ALDH1A1TSHRFDPSHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
CN-114591294-A Triazolone compound containing chloropyridine methylene as well as preparation method and application thereof 中国农业大学 2022-06-07 CN disclosed
CN-105008331-A COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN INC 2015-10-28 CN disclosed
US-6906214-B2 Preparation of aromatic organozinc compounds and composition therefore RHODIA CHIMIE (FR) 2005-06-14 US disclosed
US-20040254064-A1 Method for electrolytic heterocoupling between an aryl(pseudo) halide and an ester containing an ethylenic unsaturation, use of cobalt in order to carry out said coupling and composition therefor RHODIA CHIMIE (FR) 2004-12-16 US disclosed
US-20040236155-A1 Preparation of aromatic organozinc compounds and composition therefor SHASUN PHARMA SOLUTIONS, INC. 2004-11-25 US disclosed
US-6808655-B1 ELECTROLYSIS ON AN INERT CATHODE LIQUID MIXTURE OF COBALT SALT, ZINC SALT, AND ORGANIC HALIDE; RECOVERING RHODIA CHIMIE (FR) 2004-10-26 US disclosed
US-20040186328-A1 Process of heterocoupling by electrolytic microbattery, use of cobalt for implementing said coupling and composition for doing so RHODIA CHIMIE (FR) 2004-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040186328-A1 Process of heterocoupling by electrolytic microbattery, use of cobalt for implementing said coupling and composition for doing so HCN2, HCN1, TET2 DNM1 459/4885ALDH1A1 1250/4885TDP1 3905/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 DNM1 4122/4885ALDH1A1 983/4885TDP1 4760/4885
US-20040236155-A1 Preparation of aromatic organozinc compounds and composition therefor SLC39A11, SLC39A7, SLC30A7 DNM1 3887/4885ALDH1A1 2019/4885TDP1 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.