Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.67 |
| ▸ | GRM5 | P41594 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707099 | 0.88 | P2RX7 (0.65) | P2RX7GRM5LMNAHTR1AHTR2A | |
| SCHEMBL7654754 | 0.87 | LMNA (0.66) | P2RX7LMNACNR1ALDH1A1HPGD | |
| SCHEMBL30695493 | 0.87 | P2RX7 (0.63) | P2RX7GRM5LMNAHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL10709499 | 0.85 | P2RX7 (0.66) | P2RX7GRM5LMNAHTR1AHTR2A | |
| Tetrabuthylammonium SCHEMBL6027186 | 0.85 | P2RX7 (0.50) | P2RX7GRM5LMNACNR1HTR1A | |
| SCHEMBL12163955 | 0.84 | P2RX7 (0.69) | P2RX7GRM5LMNACNR1CTSA | |
| SCHEMBL6027124 | 0.84 | P2RX7 (0.59) | P2RX7GRM5LMNAALDH1A1HPGD | |
| SCHEMBL9967794 | 0.83 | HPGD (0.62) | P2RX7GRM5LMNACNR1HTR1A | |
| SCHEMBL22811277 | 0.83 | P2RX7 (0.67) | P2RX7GRM5LMNAHTR1AHTR2A | |
| SCHEMBL4283563 | 0.81 | GRM5 (0.47) | P2RX7GRM5LMNACNR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227026-A1 | HETEROCYCLIC COMPOUNDS AS PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| WO-2023232069-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都苑东生物制药股份有限公司 | 2023-12-07 | — | — | WO | disclosed |
| WO-2018069468-A1 | BENZOTHIAZOLE DERIVATIVES AS DYRK1 INHIBITORS | PHARMASUM THERAPEUTICS AS (NO) | 2018-04-19 | — | — | WO | disclosed |
| US-20050148631-A1 | Amino heterocyclyl inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | AGOURON PHARMACEUTICALS, INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148631-A1 | Amino heterocyclyl inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B11, HSD11B2 | P2RX7 4589/4885GRM5 1735/4885LMNA 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.