Sugi Predict

Sugi Predict / Compounds / SCHEMBL6452004

SCHEMBL6452004

SCHEMBL6452004

CN(C)C(=O)Nc1ccccc1Oc1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ TSHR P16473 1/20 0.53
▸ KMT2A Q03164 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ HTR2A P28223 2/20 0.49
▸ SLC6A4 P31645 2/20 0.49
▸ SLC6A2 P23975 1/20 0.49
▸ SLC6A3 Q01959 1/20 0.49
▸ ALDH1A1 P00352 3/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ GPR55 Q9Y2T6 1/20 0.48
▸ LMNA P02545 3/20 0.48
▸ POLB P06746 2/20 0.48
▸ ADRA2C P18825 1/20 0.48
▸ CACNA1H O95180 1/20 0.47
▸ CACNA1B Q00975 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ GAA P10253 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16316797 0.85 L3MBTL1 (0.56) L3MBTL1TDP1KMT2AMEN1ALDH1A1
SCHEMBL10627227 0.84 PNLIP (0.50) L3MBTL1TDP1TSHRKMT2AMEN1
SCHEMBL9575719 0.84 XIAP (0.46) L3MBTL1TSHRKMT2AMEN1SLC6A4
SCHEMBL11809564 0.83 P2RY1 (0.60) L3MBTL1TSHRKMT2AMEN1ALDH1A1
SCHEMBL11688775 0.81 LIPE (0.50) L3MBTL1TDP1TSHRKMT2AMEN1
SCHEMBL15911145 0.81 L3MBTL1 (0.63) L3MBTL1TDP1KMT2AMEN1ALDH1A1
SCHEMBL8183410 0.81 L3MBTL1 (0.53) L3MBTL1TDP1TSHRKMT2AMEN1
SCHEMBL14521772 0.81 L3MBTL1 (0.60) L3MBTL1TDP1KMT2AMEN1HTR2A
SCHEMBL8673088 0.78 TSHR (0.48) L3MBTL1TSHRKMT2AMEN1HTR2A
SCHEMBL7088595 0.78 ALDH1A1 (0.57) L3MBTL1KMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050054531-A1 N-(phosphonomethyl) glycine (glyphosate) salt, a preparation process thereof, a concentrate composition and a phytotoxic formulation comprising it, and a method to combat weeds in a crop with a formulation thereto REPOSO S.A.I.C. (AR) 2005-03-10 — — US disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 — — US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 — — US disclosed
EP-0621863-B1 SUBSTITUTED PYRIDINECARBOXYLIC ACID DERIVATIVES AS HERBICIDES ROHM & HAAS (US) 1999-09-15 — — EP disclosed
US-5877119-A HERBICIDE ROHM AND HAAS COMPANY (US) 1999-03-02 — — US disclosed
EP-0553307-B1 HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES MONSANTO CO (US) 1998-12-09 — — EP disclosed
EP-0603240-B1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLUREAS MONSANTO CO (US) 1998-12-02 — — EP disclosed
US-5843867-A Substituted pyridine compounds ROHM AND HAAS COMPANY (US) 1998-12-01 — — US disclosed
US-5824625-A HERBICIDES, HETEROCYCLIC GROUP(S) ATTACHED TO PYRIDINE RING ROHM AND HAAS COMPANY 1998-10-20 — — US disclosed
US-5773389-A HERBICIDES AND KILLING VEGETATION ROHM AND HAAS COMPANY (US) 1998-06-30 — — US disclosed
US-4035176-A POSTEMERGENT HERBICIDES, RIPENERS MONSANTO COMPANY (US) 1977-07-12 — — US disclosed
US-4029687-A HERBICIDES CIBA-GEIGY AG (CH) 1977-06-14 — — US disclosed
US-4013450-A Herbicidal ureido containing carbanilates MONSANTO COMPANY (US) 1977-03-22 — — US disclosed
US-4004914-A HERBICIDES CIBA-GEIGY AG (CH) 1977-01-25 — — US disclosed
US-3991095-A HERBICIDES MONSANTO COMPANY (US) 1976-11-09 — — US disclosed
US-3979202-A Meta-bifunctional benzenes and herbicidal compositions MONSANTO COMPANY (US) 1976-09-07 — — US disclosed
US-3977860-A PHYTOTOXICANTS MONSANTO COMPANY (US) 1976-08-31 — — US disclosed
US-3970695-A N-(perfluoroacyl)-N-phosphonomethyl glycine compounds, method of preparing same MONSANTO COMPANY (US) 1976-07-20 — — US disclosed
US-3962307-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 — — US disclosed
US-3951641-A Use of N-(4-isopropoxy-3-chlorophenyl)-N'-methyl-N'-methoxyurea for control of weeds in maize cultures CIBA-GEIGY AG (CH) 1976-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054531-A1 N-(phosphonomethyl) glycine (glyphosate) salt, a preparation process thereof, a concentrate composition and a phytotoxic formulation comprising it, and a method to combat weeds in a crop with a formulation thereto PHOSPHO1, GNMT, AGL L3MBTL1 1353/4885TDP1 1160/4885TSHR 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.