SCHEMBL645284

SCHEMBL645284

CCCC(C)(CC)OC(=O)CCC(=O)OC(C)(CC)CCC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
LMNA P02545 4/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 3/20 0.33
MLYCD O95822 1/20 0.32
GAA P10253 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
CYP3A4 P08684 1/20 0.30
NFKB1 P19838 1/20 0.30
ADRA1A P35348 1/20 0.30
RAB9A P51151 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28139317 0.92 EGLN1 (0.38) ALDH1A1LMNAHSD17B10TSHRCYP1A2
SCHEMBL19594671 0.91 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10TDP1
SCHEMBL16010233 0.88 LMNA (0.37) ALDH1A1LMNA
SCHEMBL11111552 0.87 GAA (0.36) ALDH1A1LMNAHSD17B10TSHRGAA
SCHEMBL28422861 0.87 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10TSHRGAA
SCHEMBL20919314 0.87 LMNA (0.50) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL28030481 0.86 LMNA (0.36) ALDH1A1LMNAMLYCD
SCHEMBL4929886 0.83 LMNA (0.33) LMNAHSD17B10
SCHEMBL14013021 0.83 FFAR3 (0.41) ALDH1A1LMNAHSD17B10TSHRCYP1A2
SCHEMBL14990971 0.82 LMNA (0.38) ALDH1A1LMNAHSD17B10TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2723750-B1 DIKETOPYRROLOPYRROLE OLIGOMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES CLAP CO LTD (KR) 2022-08-10 EP disclosed
EP-2751855-B1 DIKETOPYRROLOPYRROLE OLIGOMERS AND COMPOSITIONS, COMPRISING DIKETOPYRROLOPYRROLE OLIGOMERS BASF SE (DE) 2020-10-28 EP disclosed
EP-2216312-B1 PROCESS FOR PRODUCING ORGANIC COMPOUND M TECHNIQUE CO LTD (JP) 2019-05-01 EP disclosed
EP-2184109-B1 METHOD FOR PRODUCING NANOPARTICLES BY FORCED ULTRA-THIN FILM ROTARY PROCESSING M TECHNIQUE CO LTD (JP) 2017-08-23 EP disclosed
CN-106574057-A High melt strength polypropylene and extrusion process for maintaining melt strength 埃克森美孚化学专利公司 2017-04-19 CN disclosed
US-9211510-B2 Method for producing nanoparticles by forced ultrathin film rotary processing M. TECHNIQUE CO., LTD. (JP) 2015-12-15 US disclosed
EP-2751855-A1 DIKETOPYRROLOPYRROLE OLIGOMERS AND COMPOSITIONS, COMPRISING DIKETOPYRROLOPYRROLE OLIGOMERS BASF SE (DE) 2014-07-09 EP disclosed
EP-2723750-A1 DIKETOPYRROLOPYRROLE OLIGOMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2014-04-30 EP disclosed
US-8592498-B2 Method for producing organic compound and organic compound obtained by the method M. TECHNIQUE CO., LTD. (JP) 2013-11-26 US disclosed
WO-2013030325-A1 DIKETOPYRROLOPYRROLE OLIGOMERS AND COMPOSITIONS, COMPRISING DIKETOPYRROLOPYRROLE OLIGOMERS BASF SE (DE) 2013-03-07 WO disclosed
US-6566519-B2 Reacting succinic diester with nitrile CLARIANT INTERNATIONAL LTD. (CH) 2003-05-20 US disclosed
WO-2003022847-A2 PROCESS FOR THE DIRECT PREPARATION OF PYRROLO[3,4-C]PYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-03-20 WO disclosed
WO-2003022848-A2 PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-03-20 WO disclosed
EP-0962499-B1 Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles CIBA SC HOLDING AG (CH) 2003-03-05 EP disclosed
US-20020010331-A1 Reacting succinic diester with nitrile CLARIANT GMBH 2002-01-24 US disclosed
EP-0962499-A2 Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles Ciba SC Holding AG (CH) 1999-12-08 EP disclosed
US-4749795-A Phenyl substituted pyrrolinones CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
US-4720305-A Mixtures of pigments CIBA-GEIGY CORPORATION (US) 1988-01-19 US disclosed
US-4681971-A Phenyl substituted aminodicarboxylate esters CIBA-GEIGY CORPORATION (US) 1987-07-21 US disclosed
US-4579949-A REACTING DISUCCINATE WITH NITRILES CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010331-A1 Reacting succinic diester with nitrile SDHA, QDPR, SDHB ALDH1A1 790/4885LMNA 4110/4885HSD17B10 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.