Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453539 | 0.85 | KMT2A (0.59) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL7181724 | 0.84 | ALDH1A1 (0.52) | L3MBTL1ATMTDP1CYP19A1ALDH1A1 | |
| SCHEMBL4669025 | 0.81 | TDP1 (0.61) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL7394259 | 0.81 | TDP1 (0.61) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL27691637 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL10905589 | 0.79 | ATM (0.59) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL11301145 | 0.79 | TDP1 (0.59) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL3112767 | 0.79 | KEAP1 (0.62) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL7953016 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ATMTDP1PBRM1CYP19A1 | |
| SCHEMBL7046114 | 0.77 | L3MBTL1 (0.65) | L3MBTL1ATMTDP1PBRM1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347373-A | Derivatives of 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole | TURCONI FRANCO | 1982-08-31 | — | — | US | disclosed |
| EP-0036684-A1 | Derivatives of 4-methyl-5-(2-aminoethyl)-thiomethyl-imidazole having therapeutic activity | Turconi, Franco (IT) | 1981-09-30 | — | — | EP | disclosed |