SCHEMBL645500

SCHEMBL645500

COc1cc(C=CC(=O)OCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C)cc(OC)c1OC

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 11/20 0.56
ABCG2 Q9UNQ0 10/20 0.56
ABCC1 P33527 9/20 0.56
ALOX5 P09917 2/20 0.52
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MET P08581 2/20 0.50
HTR1A P08908 2/20 0.50
GAA P10253 1/20 0.50
HTT P42858 1/20 0.50
HPGD P15428 1/20 0.50
HTR2C P28335 1/20 0.50
HSD17B10 Q99714 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440564 0.96 ABCB1 (0.58) ABCB1ABCG2ABCC1ALOX5
SCHEMBL9119106 0.91 ABCB1 (0.56) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL9440544 0.87 ABCB1 (0.58) ABCB1ABCG2ABCC1ALOX5
SCHEMBL527316 0.83 ABCB1 (0.51) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL527317 0.83 ABCB1 (0.51) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL17459718 0.82 ALOX5 (0.67) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL17459720 0.82 ALOX5 (0.67) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL647362 0.81 ALDH1A1 (0.47) ABCB1ABCG2ABCC1KDM4EALDH1A1
SCHEMBL21817003 0.80 ABCB1 (0.64) ABCB1ABCG2ABCC1ALOX5KDM4E
SCHEMBL21817002 0.80 ABCB1 (0.64) ABCB1ABCG2ABCC1ALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3204887-A None JP disclosed
US-12383476-B2 W/O/W emulsion composition SHISEIDO COMPANY, LTD. (JP) 2025-08-12 US disclosed
WO-2024142892-A1 W/O/W EMULSIFIED COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
WO-2024142969-A1 WATER-IN-OIL EMULSION COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
US-20240139085-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, DISPERSION LIQUID, COSMETIC PREPARATION, AND METHOD FOR PRODUCING SURFACE-MODIFIED ZINC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2024-05-02 US disclosed
WO-2024080367-A1 POLYSILOXANE-COATED METAL OXIDE PARTICLES, DISPERSION LIQUID, COMPOSITION, COSMETIC, AND METHOD FOR PRODUCING POLYSILOXANE-COATED METAL OXIDE PARTICLES 住友大阪セメント株式会社 2024-04-18 WO disclosed
EP-4296232-A1 SURFACE-MODIFIED ZINC OXIDE PAPRTICLES, DISPERSION LIQUID, COSMETIC PREPARATION, AND METHOD FOR PRODUCING SURFACE-MODIFIED ZINC OXIDE PARTICLES Sumitomo Osaka Cement Co., Ltd. (JP) 2023-12-27 EP disclosed
WO-2023210618-A1 SURFACE-TREATED ZINC OXIDE PARTICLES, DISPERSION LIQUID, COSMETIC MATERIAL, METHOD FOR PRODUCING SURFACE-TREATED ZINC OXIDE PARTICLES 住友大阪セメント株式会社 2023-11-02 WO disclosed
WO-2023190487-A1 SURFACE-MODIFIED ZINC OXIDE PARTICLES, DISPERSION LIQUID AND COSMETIC PREPARATION 住友大阪セメント株式会社 2023-10-05 WO disclosed
EP-4253323-A1 ZINC OXIDE POWDER, DISPERSION LIQUID, COATING MATERIAL, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2023-10-04 EP disclosed
US-9403691-B1 Zinc oxide powder, dispersion, paint, and cosmetic material SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2016-08-02 US disclosed
EP-1974717-B1 DISPERSION OF FINE TITANIUM OXIDE PARTICLES AND COSMETIC PREPARATION CONTAINING THE SAME SHISEIDO CO LTD (JP) 2016-03-23 EP disclosed
US-8119108-B2 Dispersion of microparticulate titanium oxide and cosmetics containing the same SHISEIDO CO., LTD. (JP) 2012-02-21 US disclosed
US-20090169496-A1 Dispersion Of Microparticulate Titanium Oxide And Cosmetics Containing The Same SHISEIDO CO., LTD. (JP) 2009-07-02 US disclosed
EP-1974717-A1 DISPERSION OF FINE TITANIUM OXIDE PARTICLES AND COSMETIC PREPARATION CONTAINING THE SAME Shiseido Company, Limited (JP) 2008-10-01 EP disclosed
EP-0350314-B1 Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. SHISEIDO CO LTD (JP) 1995-12-13 EP disclosed
US-5315022-A Sunscreen SHISEIDO COMPANY LTD. (JP) 1994-05-24 US disclosed
US-5093511-A SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT SHISEIDO COMPANY, LTD. (JP) 1992-03-03 US disclosed
JP-H03204887-A PRODUCTION OF SILICONE BASED CONNAMIC ACID DERIVATIVE SHISEIDO CO LTD 1991-09-06 JP disclosed
EP-0350314-A2 Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. SHISEIDO COMPANY LIMITED (JP) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090169496-A1 Dispersion Of Microparticulate Titanium Oxide And Cosmetics Containing The Same THPO, TPSD1, TPSG1 ABCB1 4119/4885ABCG2 4607/4885ABCC1 4814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.