SCHEMBL645554

SCHEMBL645554

Cc1ccc2cc(N(C)C)ccc2n1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.61
TERT O14746 1/20 0.57
APP P05067 1/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.57
CASP6 P55212 1/20 0.57
PSMB5 P28074 7/20 0.54
EGFR P00533 2/20 0.50
APAF1 O14727 1/20 0.47
PDE3B Q13370 1/20 0.45
PDE3A Q14432 1/20 0.45
SLC2A1 P11166 1/20 0.42
KDM1A O60341 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589893 1.00 CYP1A2 (0.61) CYP1A2TERTAPPKDM4ELMNA
SCHEMBL2672636 0.88 TERT (0.69) CYP1A2TERTAPPKDM4ELMNA
SCHEMBL2222093 0.85 CYP1A2 (0.63) CYP1A2TERTAPPKDM4ELMNA
SCHEMBL12647016 0.80 APP (0.71) TERTAPPPSMB5EGFRAPAF1
SCHEMBL11322348 0.79 TERT (0.61) CYP1A2TERTKDM4ELMNAPOLB
SCHEMBL17709258 0.78 APP (0.55) TERTAPPKDM4EPOLBCASP6
SCHEMBL5440195 0.78 TERT (0.55) TERTAPPPSMB5EGFRAPAF1
SCHEMBL11375051 0.77 CYP1A2 (0.49) CYP1A2TERTAPPKDM4ELMNA
SCHEMBL12566471 0.77 TERT (0.64) TERTAPPKDM4EPSMB5EGFR
SCHEMBL29444268 0.76 CYP1A2 (1.00) CYP1A2KDM4ELMNAPOLBCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4334008-A PHOTORESISTS BARD LABORATORIES, INC. (US) 1982-06-08 US claimed
US-4312934-A REACTIONOF AROMATIC AMINE OR HYDROXYLAMINE WITH POLYMER CONTAINING NITRATE GROUPS BARD LABORATORIES, INC. (US) 1982-01-26 US claimed
US-4049457-A WITH AN ORGANIC ACID BARD LABORATORIES, INC. (US) 1977-09-20 US claimed
CN-116589404-B Photosensitizer targeting beta amyloid protein and preparation method and application thereof 华南理工大学 2026-05-15 CN disclosed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
EP-3442956-B1 A PROCESS FOR THE PREPARATION OF PYRVINIUM PAMOATE AND CRYSTALLINE FORMS THEREOF URQUIMA SA (ES) 2024-03-27 EP disclosed
CN-116589404-A Photosensitizer targeting beta amyloid protein and preparation method and application thereof 华南理工大学 2023-08-15 CN disclosed
US-20230045778-A9 HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR BRILLIANT LIGHT POWER, INC. (US) 2023-02-09 US disclosed
CN-111978248-A Multi-site modifiable aggregation-induced emission quinoline nitrile derivative, and preparation method and application thereof 华东理工大学 2020-11-24 CN disclosed
US-20200299130-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. (US) 2020-09-24 US disclosed
US-10646416-B2 Microcapsules containing a gas-releasing photolabile compound and uses thereof FIRMENICH SA (CH) 2020-05-12 US disclosed
WO-2008128100-A1 SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-10-23 WO disclosed
CN-101106992-A Novel quinolinium salts and derivatives IMMUSOL INC (US) 2008-01-16 CN disclosed
EP-1841428-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES Immusol Incorporated (US) 2007-10-10 EP disclosed
WO-2006078754-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES IMMUSOL INCORPORATED (US) 2006-07-27 WO disclosed
US-4264710-A AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4014877-A MICROBIOCIDES RIKER LABORATORIES, INC. (US) 1977-03-29 US disclosed
US-4001243-A ANTI-MICROBIAL RIKER LABORATORIES, INC. (US) 1977-01-04 US disclosed
US-3985882-A ADMISTERING RIKER LABORATORIES, INC. (US) 1976-10-12 US disclosed
US-3969463-A MICROBIOCIDE RIKER LABORATORIES, INC. (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10646416-B2 Microcapsules containing a gas-releasing photolabile compound and uses thereof ALOX5, TRPA1, FASN CYP1A2 1863/4885TERT 4314/4885APP 621/4885
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 CYP1A2 1592/4885TERT 2096/4885APP 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.