Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465506 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6459062 | 0.74 | THRB (0.40) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL799900 | 0.73 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL19625332 | 0.70 | RAB9A (0.58) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2225642 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7705459 | 0.69 | LOXL2 (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5646258 | 0.69 | KDM4E (0.53) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7705461 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL19625353 | 0.67 | ATP4A (0.49) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2228668 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894046-B2 | IL-5 inhibiting 6-azauracil derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-05-17 | — | — | US | disclosed |
| EP-1114046-B1 | INTERLEUKIN-5 INHIBITING 6-AZAURACIL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-23 | — | — | EP | disclosed |
| EP-0987265-A1 | Interleukin-5 inhibiting 6-azauracil derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-03-22 | — | — | EP | disclosed |