Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.32 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423305 | 0.87 | GABRA1 (0.39) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL541137 | 0.82 | POLB (0.48) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL21203054 | 0.77 | CYP2C9 (0.48) | POLBALDH1A1TP53CYP1A2CYP2C9 | |
| SCHEMBL10411551 | 0.76 | CA2 (0.52) | POLBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7941748 | 0.75 | POLB (0.56) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL7795745 | 0.74 | POLB (0.50) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL16022232 | 0.71 | ALDH1A1 (0.52) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL9799571 | 0.70 | POLB (0.39) | POLBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10342450 | 0.70 | POLB (0.70) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL5158750 | 0.70 | POLB (0.50) | POLBALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669960-B1 | POLYUREA POLYMERS HAVING IMPROVED HIGH TEMPERATURE STABILITY AND METHOD OF MAKING SAME | DOW CHEMICAL CO (US) | 1998-09-02 | — | — | EP | claimed |
| US-5525681-A | MIXING POLYISOCYANATE, POLYEPOXIDE, POLYAMINE, HEATING, POSTCURING AT HIGHER TEMPERATURE | THE DOW CHEMICAL COMPANY (US) | 1996-06-11 | — | — | US | claimed |
| EP-0669960-A1 | POLYUREA POLYMERS HAVING IMPROVED HIGH TEMPERATURE STABILITY AND METHOD OF MAKING SAME | THE DOW CHEMICAL COMPANY (US) | 1995-09-06 | — | — | EP | claimed |
| WO-1994012573-A1 | POLYUREA POLYMERS HAVING IMPROVED HIGH TEMPERATURE STABILITY AND METHOD OF MAKING SAME | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | claimed |
| US-5057625-A | Heating mixture of toluenediamine and aluminum halide compounds reacting with isobutylene | ETHYL CORPORATION (US) | 1991-10-15 | — | — | US | claimed |
| US-20050096403-A1 | Method of making polyurea containing automobile body parts | JAMES ALLAN (CA) | 2005-05-05 | — | — | US | disclosed |
| EP-1242525-B1 | BLISTER-RESISTANT MOLDED POLYUREA POLYMER AND METHOD OF MAKING A BLISTER-RESISTANT MOLDED POLYUREA POLYMER | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6723821-B2 | REACT WITH A TERMINAL AMINO GROUP OF POLYAMINE WITH AN EPOXY COMPOUND, DECYCLIZING; FORMING AN INTERMEDIATE FOR POLYUREA COATINGS | HEHR, INTERNATIONAL INC. | 2004-04-20 | — | — | US | disclosed |
| US-6613864-B1 | Using butylene oxide adduct | DOW GLOBAL TECHNOLOGIES INC. | 2003-09-02 | — | — | US | disclosed |
| EP-1161472-B1 | HIGH TEMPERATURE RESISTANT POLYURETHANE POLYMERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-01-08 | — | — | EP | disclosed |
| US-20020183450-A1 | Polyamine epoxide adduct | HEHR INTERNATIONAL INC. | 2002-12-05 | — | — | US | disclosed |
| EP-1242525-A1 | BLISTER-RESISTANT MOLDED POLYUREA POLYMER AND METHOD OF MAKING A BLISTER-RESISTANT MOLDED POLYUREA POLYMER | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-0177916-B1 | MONO-TERTIARY-ALKYLATED TOLUENEDIAMINE AND DERIVATIVES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0178583-B1 | POLYURETHANE SYSTEMS USING MONOTERTIARY-ALKYLTOLUENEDIAMINE AS A CROSS LINKER | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4816543-A | REACTIN INJECTION MOLDING MATERIALS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-03-28 | — | — | US | disclosed |
| US-4745223-A | CHAIN EXTENDERS FOR POLYUREAS AND POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4740620-A | HIGH SELECTIVITY TO THE ORTHO POSITION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0226781-A1 | Alkylation of aromatic amines in the presence of acidic, crystalline molecular sieves | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1987-07-01 | — | — | EP | disclosed |
| EP-0178583-A1 | Polyurethane systems using monotertiary-alkyltoluenediamine as a cross linker | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-04-23 | — | — | EP | disclosed |
| EP-0177916-A1 | Mono-tertiary-alkylated toluenediamine and derivatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-04-16 | — | — | EP | disclosed |