SCHEMBL6458908

SCHEMBL6458908

O=C1CCC2CC(=O)CCC2C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SHBG P04278 2/20 0.33
MPO P05164 1/20 0.32
TRIM24 O15164 2/20 0.32
TRIM33 Q9UPN9 2/20 0.32
ESR2 Q92731 1/20 0.31
MAPT P10636 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14791326 1.00 SHBG (0.33) SHBGMPOTRIM24TRIM33ESR2
SCHEMBL6458899 1.00 SHBG (0.33) SHBGMPOTRIM24TRIM33ESR2
Ethylene SCHEMBL10472915 0.94 SHBG (0.32) SHBGMPO
SCHEMBL10389935 0.94 MAPK1 (0.32) SHBGMPO
SCHEMBL10286415 0.94
SCHEMBL16466258 0.94 MAPK1 (0.32) SHBGMPO
SCHEMBL11442767 0.90 SHBG (0.33) SHBGMPOTRIM24TRIM33ESR2
SCHEMBL11442768 0.90 SHBG (0.33) SHBGMPOTRIM24TRIM33ESR2
SCHEMBL11593525 0.89 ALDH1A1 (0.35) SHBGTRIM24TRIM33MAPTALDH1A1
SCHEMBL6889662 0.89 ALDH1A1 (0.42) SHBGTRIM24TRIM33MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732569-B Liquid crystalline compound having dibenzothiophene ring, liquid crystal composition, and liquid crystal display element 捷恩智株式会社 2024-07-09 CN disclosed
CN-117263781-A Compound, liquid crystal composition and liquid crystal display element 捷恩智株式会社 2023-12-22 CN disclosed
CN-110300746-B Liquid crystalline compound, liquid crystal composition, and liquid crystal display element 捷恩智株式会社 2023-08-15 CN disclosed
CN-114787130-A Compound, liquid crystal composition and liquid crystal display element 捷恩智株式会社 2022-07-22 CN disclosed
CN-107428651-B Liquid crystalline compound, liquid crystal composition, liquid crystal-encapsulated composite fiber, fiber aggregate, fiber composite, and liquid crystal display element 捷恩智株式会社 2021-06-22 CN disclosed
CN-111732569-A Liquid crystalline compound having dibenzothiophene ring, liquid crystal composition, and liquid crystal display element 捷恩智株式会社 2020-10-02 CN disclosed
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed
US-10570334-B2 Liquid crystal compound, liquid crystal composition, composite material with encapsulated liquid crystal, and liquid crystal display device using same JNC CORPORATION (JP) 2020-02-25 US disclosed
US-10570334-B2 Liquid crystal compound, liquid crystal composition, composite material with encapsulated liquid crystal, and liquid crystal display device using same JNC CORPORATION (JP) 2020-02-25 US disclosed
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-09-10 US disclosed
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-09-10 US disclosed
US-7241551-B2 Positive-working resist composition FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed
US-7241551-B2 Positive-working resist composition FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed
JP-2000239214-A DECAHYDRONAPHTHALENE DERIVATIVE AND ITS PRODUCTION DAINIPPON INK & CHEM INC 2000-09-05 JP disclosed
US-4921923-A Ethers of oligomeric phenol-diketone condensation products and a vinyl-benzyl compound ALLIED SIGNAL INC. (US) 1990-05-01 US disclosed
EP-0343798-A1 Preparation of aromatic compounds and derivatives thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-29 EP disclosed
EP-0049953-B1 4-(SUBSTITUTED PHENYL)-NAPHTHALEN-2(1H)-ONES AND 2-OLS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PFIZER INC. (US) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DRD1, CNKSR1, DRG1 SHBG 3432/4885MPO 3324/4885TRIM24 2249/4885
US-10570334-B2 Liquid crystal compound, liquid crystal composition, composite material with encapsulated liquid crystal, and liquid crystal display device using same SOD1, SLC39A11, MTX1 SHBG 1026/4885MPO 221/4885TRIM24 1912/4885
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 SHBG 3268/4885MPO 3916/4885TRIM24 3109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.