Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468211 | 0.87 | SMN1; SMN2 (0.57) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL6466633 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL6461792 | 0.80 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL6460154 | 0.77 | TP53 (0.54) | MEN1KMT2AMAPTPPARASMN1; SMN2 | |
| SCHEMBL11140628 | 0.76 | MEN1 (0.57) | MEN1KMT2AMAPTPPARASMN1; SMN2 | |
| SCHEMBL6465235 | 0.76 | RECQL (0.55) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL6465991 | 0.73 | LMNA (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10890123 | 0.71 | KDM4E (0.53) | MEN1KMT2AMAPTPPARASMN1; SMN2 | |
| SCHEMBL10889203 | 0.71 | HTT (0.59) | MEN1KMT2AMAPTPPARASMN1; SMN2 | |
| SCHEMBL10885852 | 0.71 | MEN1 (0.54) | MEN1KMT2AMAPTPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090299-A2 | CARBAMATES AS HIV ANTI-VIRAL AGENTS | WYETH (US) | 2005-09-29 | — | — | WO | claimed |
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | claimed |
| WO-2005090299-A2 | CARBAMATES AS HIV ANTI-VIRAL AGENTS | WYETH (US) | 2005-09-29 | — | — | WO | disclosed |
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | RNASEH1, CTSH, RNASE1 | MEN1 4110/4885KMT2A 593/4885MAPT 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.