Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461792 | 0.86 | MEN1 (0.41) | ALDH1A1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL6460158 | 0.81 | MEN1 (0.51) | ALDH1A1L3MBTL1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6466625 | 0.77 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL11148177 | 0.76 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL6468211 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1L3MBTL1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6465991 | 0.73 | LMNA (0.57) | ALDH1A1L3MBTL1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10885570 | 0.69 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1NPC1RAB9ACACNA1G | |
| SCHEMBL25658467 | 0.69 | NPC1 (0.66) | ALDH1A1L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL2095756 | 0.68 | HPGD (0.73) | ALDH1A1L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL2095753 | 0.68 | HPGD (0.68) | ALDH1A1L3MBTL1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090299-A2 | CARBAMATES AS HIV ANTI-VIRAL AGENTS | WYETH (US) | 2005-09-29 | — | — | WO | claimed |
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | claimed |
| WO-2005090299-A2 | CARBAMATES AS HIV ANTI-VIRAL AGENTS | WYETH (US) | 2005-09-29 | — | — | WO | disclosed |
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | RNASEH1, CTSH, RNASE1 | ALDH1A1 2591/4885L3MBTL1 2032/4885NPC1 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.