Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460267 | 1.00 | SIGMAR1 (0.31) | SIGMAR1MEN1KMT2ACNR1PDE2A | |
| SCHEMBL6457618 | 0.85 | IDO1 (0.33) | CNR1DRD2 | |
| SCHEMBL6457624 | 0.85 | IDO1 (0.33) | CNR1DRD2 | |
| SCHEMBL6459396 | 0.85 | SLC6A4 (0.39) | LRRK2 | |
| SCHEMBL6459394 | 0.85 | SLC6A4 (0.39) | LRRK2 | |
| SCHEMBL6460335 | 0.84 | HTR2C (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3DRD2 | |
| SCHEMBL6460330 | 0.84 | HTR2C (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3DRD2 | |
| SCHEMBL6459954 | 0.83 | OPRM1 (0.35) | MEN1KMT2ACNR1DRD2 | |
| SCHEMBL6459949 | 0.83 | OPRM1 (0.35) | MEN1KMT2ACNR1DRD2 | |
| SCHEMBL6456698 | 0.83 | ACHE (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |