Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047182 | 0.91 | DAGLA (0.39) | DAGLAUSP2TP53ALOX15TSHR | |
| SCHEMBL6461813 | 0.85 | P2RX7 (0.40) | DAGLAEPHX1EPHX2 | |
| SCHEMBL6062848 | 0.84 | DAGLA (0.39) | DAGLAUSP2TP53ALOX15TSHR | |
| SCHEMBL7567535 | 0.81 | DAGLA (0.43) | DAGLACES1 | |
| SCHEMBL6467926 | 0.80 | DAGLA (0.44) | DAGLANPSR1CES1ALDH1A1MAPT | |
| SCHEMBL6467199 | 0.78 | DAGLA (0.41) | DAGLAMAPK1CES1EPHX2NPC1 | |
| SCHEMBL7047180 | 0.77 | P2RX7 (0.37) | DAGLAEPHX1EPHX2 | |
| SCHEMBL7049295 | 0.72 | DAGLA (0.41) | DAGLACES1MAPT | |
| SCHEMBL6475177 | 0.71 | DAGLA (0.47) | DAGLACES1 | |
| SCHEMBL6475520 | 0.71 | DAGLA (0.50) | DAGLACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |