Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049295 | 0.90 | DAGLA (0.41) | DAGLACES1KMT2AMAPT | |
| SCHEMBL7567535 | 0.83 | DAGLA (0.43) | DAGLACES1KMT2ALMNAPKM | |
| SCHEMBL6461816 | 0.80 | DAGLA (0.42) | DAGLACES1ALDH1A1NPSR1MAPT | |
| SCHEMBL6467199 | 0.80 | DAGLA (0.41) | DAGLACES1LMNAGAAPKM | |
| SCHEMBL6475177 | 0.77 | DAGLA (0.47) | DAGLACES1KMT2AKDM4E | |
| SCHEMBL6466207 | 0.76 | DAGLA (0.46) | DAGLACES1 | |
| SCHEMBL6461813 | 0.75 | P2RX7 (0.40) | DAGLA | |
| SCHEMBL6467249 | 0.75 | TRPV1 (0.51) | DAGLACES1GAA | |
| SCHEMBL6475520 | 0.74 | DAGLA (0.50) | DAGLACES1 | |
| SCHEMBL7558531 | 0.73 | DAGLA (0.39) | DAGLAKMT2APOLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |