Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047180 | 0.91 | P2RX7 (0.37) | P2RX7CTSLDAGLAEPHX2ABCB11 | |
| SCHEMBL6461816 | 0.85 | DAGLA (0.42) | DAGLAEPHX2EPHX1 | |
| SCHEMBL6467199 | 0.84 | DAGLA (0.41) | DAGLAEPHX2 | |
| SCHEMBL7567535 | 0.84 | DAGLA (0.43) | DAGLA | |
| SCHEMBL7047182 | 0.77 | DAGLA (0.39) | DAGLAEPHX2EPHX1 | |
| SCHEMBL7558531 | 0.77 | DAGLA (0.39) | DAGLA | |
| SCHEMBL6467926 | 0.75 | DAGLA (0.44) | DAGLA | |
| SCHEMBL7047979 | 0.73 | TBXA2R (0.41) | DAGLA | |
| SCHEMBL7044843 | 0.73 | L3MBTL1 (0.39) | DAGLAEPHX2 | |
| SCHEMBL7186571 | 0.72 | MASP2 (0.38) | DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |