Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461987 | 0.91 | KMT2A (0.63) | ALDH1A1CYP3A4KMT2ACARM1MME | |
| SCHEMBL2236118 | 0.91 | KMT2A (0.63) | ALDH1A1CYP3A4KMT2ACARM1MME | |
| SCHEMBL1790978 | 0.91 | KMT2A (0.63) | ALDH1A1CYP3A4KMT2ACARM1MME | |
| Hydrochloric Acid SCHEMBL5966886 | 0.89 | CARM1 (0.62) | ALDH1A1CYP3A4KMT2ACARM1MME | |
| Trifluoroacetic Acid SCHEMBL10425462 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CYP3A4KMT2AMMEOPRK1 | |
| Trifluoroacetic Acid SCHEMBL7101192 | 0.88 | MMP8 (0.53) | ALDH1A1CYP3A4KMT2AMMEOPRK1 | |
| Trifluoroacetic Acid SCHEMBL14762492 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP3A4KMT2ACARM1MME | |
| SCHEMBL8935468 | 0.84 | CARM1 (0.58) | ALDH1A1KMT2ACARM1MMEPRMT6 | |
| Trifluoroacetic Acid SCHEMBL10572656 | 0.83 | ANPEP (0.55) | ALDH1A1CYP3A4KMT2AMMEOPRK1 | |
| Trifluoroacetic Acid SCHEMBL18787156 | 0.83 | CARM1 (0.52) | ALDH1A1KMT2ACARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225238-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZOÝ1,2- ¨IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2014-09-03 | — | — | EP | disclosed |
| US-8552205-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-alpha]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-08 | — | — | US | disclosed |
| US-20110224188-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-15 | — | — | US | disclosed |
| EP-2225238-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZOÝ1,2- ¨IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | Boehringer Ingelheim International GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224188-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | HPGDS, COL14A1, ARG1 | ALDH1A1 1552/4885CYP3A4 2026/4885KMT2A 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.