Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467437 | 0.86 | PTPN1 (0.41) | PTPN1PTPN2HDAC3HDAC4HDAC1 | |
| SCHEMBL6466334 | 0.83 | CCR1 (0.39) | CCR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6463648 | 0.82 | CTSS (0.39) | CCR1LMNAMAPTFAAH | |
| SCHEMBL7049302 | 0.76 | FAAH (0.40) | PTPN1LMNAMAPTFAAHCES1 | |
| SCHEMBL6465743 | 0.74 | CTSS (0.40) | CCR1LMNA | |
| Hydrochloric Acid SCHEMBL6465927 | 0.71 | ALDH1A1 (0.36) | PTPN1PTPN2HDAC3HDAC4HDAC1 | |
| SCHEMBL27753873 | 0.70 | MAPT (0.40) | PTPN1PTPN2LMNAMAPT | |
| SCHEMBL7044965 | 0.69 | ALDH1A1 (0.43) | PTPN1LMNAMAPTPPARG | |
| SCHEMBL7045440 | 0.67 | HPGD (0.41) | LMNA | |
| SCHEMBL6466904 | 0.66 | DAGLA (0.50) | USP2LMNAMAPTADORA2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |