Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 8/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463648 | 0.91 | CTSS (0.39) | CTSSCTSLCCR1LMNAKMT2A | |
| SCHEMBL6466334 | 0.90 | CCR1 (0.39) | CTSSCTSLCCR1LMNAKMT2A | |
| SCHEMBL7045920 | 0.80 | CTSL (0.40) | CTSSCTSLPTGESLMNAKMT2A | |
| SCHEMBL6462669 | 0.78 | CCR1 (0.35) | CTSSCTSLCCR1KMT2A | |
| SCHEMBL6462284 | 0.74 | PTPN1 (0.39) | CCR1LMNA | |
| SCHEMBL6467437 | 0.70 | PTPN1 (0.41) | PTGES | |
| SCHEMBL7045440 | 0.69 | HPGD (0.41) | CTSSLMNAKMT2ABACE1 | |
| SCHEMBL6465745 | 0.65 | KMT2A (0.43) | CTSSCTSLPTGESLMNAKMT2A | |
| SCHEMBL6473317 | 0.64 | MMP1 (0.40) | CTSSCTSLCCR1LMNA | |
| SCHEMBL11361820 | 0.62 | LMNA (0.50) | LMNAKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |