Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467443 | 0.86 | FAAH (0.36) | DAGLAFAAHCES1XDHMAPT | |
| SCHEMBL6466340 | 0.83 | LMNA (0.39) | DAGLAFAAHCES1XDHMAPT | |
| SCHEMBL6463655 | 0.83 | LMNA (0.39) | DAGLAFAAHCES1XDHMAPT | |
| SCHEMBL6462568 | 0.78 | METAP2 (0.37) | DAGLAFAAHCES1XDHMAPT | |
| Hydrochloric Acid SCHEMBL6466457 | 0.76 | KMT2A (0.32) | DAGLAFAAHCES1XDHNPC1 | |
| SCHEMBL6472489 | 0.74 | FAAH (0.36) | DAGLAFAAHCES1XDHMAPT | |
| SCHEMBL7049306 | 0.73 | DAGLA (0.44) | DAGLAFAAHCES1XDHMAPT | |
| Hydrochloric Acid SCHEMBL6465937 | 0.71 | FAAH (0.35) | DAGLAFAAHCES1XDHMAPT | |
| SCHEMBL6464160 | 0.71 | LMNA (0.39) | DAGLAFAAHCES1MAPTLMNA | |
| SCHEMBL6467037 | 0.71 | FAAH (0.36) | DAGLAFAAHCES1XDHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |