Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049542 | 0.89 | MAPT (0.40) | ALDH1A1MAPTLMNAPTPN2PTPN1 | |
| SCHEMBL7046906 | 0.87 | MAPT (0.43) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL6462894 | 0.87 | MEN1 (0.38) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6063046 | 0.86 | LMNA (0.36) | LMNAMEN1KMT2A | |
| SCHEMBL6063233 | 0.83 | FAAH (0.37) | FAAHCES1DAGLAALDH1A1MAPT | |
| SCHEMBL6462136 | 0.83 | FAAH (0.37) | FAAHCES1DAGLAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6465937 | 0.82 | FAAH (0.35) | FAAHCES1DAGLAALDH1A1MAPT | |
| SCHEMBL6467037 | 0.81 | FAAH (0.36) | FAAHCES1DAGLAALDH1A1MAPT | |
| SCHEMBL6466282 | 0.81 | LMNA (0.39) | FAAHCES1DAGLAMAPTLMNA | |
| SCHEMBL6061831 | 0.80 | RAB9A (0.34) | MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |