Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463422 | 0.87 | FAAH (0.41) | CTSSFAAHALOX5CYP3A4CYP2C9 | |
| SCHEMBL6461911 | 0.83 | FAAH (0.42) | CTSSFAAHALOX5LMNASMN1; SMN2 | |
| SCHEMBL6062675 | 0.76 | CTSS (0.42) | CTSSFAAHCYP3A4CYP2C9LMNA | |
| SCHEMBL7045900 | 0.76 | CTSS (0.43) | CTSSFAAHCYP3A4CYP2C9 | |
| SCHEMBL7045911 | 0.74 | EPHX2 (0.47) | CTSSFAAHLMNASMN1; SMN2TSHR | |
| SCHEMBL6466913 | 0.73 | FAAH (0.41) | CTSSFAAHCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL6061692 | 0.72 | CTSS (0.41) | CTSSFAAHCYP3A4CYP2C9LMNA | |
| SCHEMBL6466351 | 0.72 | FAAH (0.38) | CTSSFAAHCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL6463782 | 0.72 | CTSS (0.43) | CTSSFAAHCYP3A4CYP2C9LMNA | |
| SCHEMBL6471951 | 0.70 | XDH (0.43) | CTSSFAAHCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |