Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GART | P22102 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466063 | 0.88 | KDM4E (0.41) | FAAHCES1DAGLAXDHKDM4E | |
| SCHEMBL6463422 | 0.82 | FAAH (0.41) | FAAHGARTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6471951 | 0.81 | XDH (0.43) | FAAHCES1DAGLAXDHKDM4E | |
| SCHEMBL6465893 | 0.79 | GART (0.43) | FAAHCES1DAGLAXDHKDM4E | |
| SCHEMBL6464310 | 0.79 | ALDH1A1 (0.41) | FAAHCES1DAGLAXDHKDM4E | |
| SCHEMBL6461911 | 0.77 | FAAH (0.42) | FAAHCES1DAGLAGARTSMN1; SMN2 | |
| SCHEMBL6465159 | 0.74 | FAAH (0.44) | FAAHCES1DAGLAXDHGART | |
| SCHEMBL6463790 | 0.73 | CTSS (0.43) | FAAHSMN1; SMN2CTSSCYP3A4CYP2C9 | |
| SCHEMBL7047104 | 0.72 | LMNA (0.45) | FAAHCES1DAGLAXDHKDM4E | |
| SCHEMBL6475534 | 0.72 | SMN1; SMN2 (0.39) | KDM4EPOLBGARTRAB9AGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |