Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GART | P22102 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463790 | 0.87 | CTSS (0.43) | FAAHCTSSALOX5LMNASMN1; SMN2 | |
| SCHEMBL6461911 | 0.86 | FAAH (0.42) | FAAHCTSSALOX5LMNASMN1; SMN2 | |
| SCHEMBL6466913 | 0.82 | FAAH (0.41) | FAAHCTSSSMN1; SMN2GARTCYP3A4 | |
| SCHEMBL6472186 | 0.81 | KMT2A (0.38) | FAAHSMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL6467113 | 0.80 | DAGLA (0.52) | FAAHCTSSLMNASMN1; SMN2TSHR | |
| SCHEMBL6467368 | 0.80 | MAOB (0.49) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6466063 | 0.76 | KDM4E (0.41) | FAAHCTSSHTTMAPTGART | |
| SCHEMBL6061692 | 0.75 | CTSS (0.41) | FAAHCTSSLMNASMN1; SMN2HTT | |
| SCHEMBL7045911 | 0.74 | EPHX2 (0.47) | FAAHCTSSLMNASMN1; SMN2TSHR | |
| SCHEMBL6062675 | 0.73 | CTSS (0.42) | FAAHCTSSLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |