Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042863 | 0.80 | KCNA5 (0.37) | MAPTALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL7046903 | 0.80 | TBXA2R (0.35) | ALDH1A1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL7045973 | 0.79 | PSMB5 (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL7042125 | 0.79 | L3MBTL1 (0.39) | ALDH1A1RAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL7049145 | 0.79 | KCNA5 (0.38) | MAPTALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7185049 | 0.79 | MEN1 (0.35) | MAPTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL7046404 | 0.77 | MAPT (0.35) | MAPTALDH1A1TDP1GAAL3MBTL1 | |
| SCHEMBL6466202 | 0.76 | LMNA (0.36) | MAPTALDH1A1RAB9APOLBKMT2A | |
| SCHEMBL6467927 | 0.76 | GAA (0.44) | MAPTALDH1A1RAB9APOLBKMT2A | |
| SCHEMBL6463781 | 0.74 | SMN1; SMN2 (0.39) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |