Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | GBA1 | P04062 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455341 | 0.86 | KDM4E (0.76) | KDM4ESMN1; SMN2TP53RAB9AKMT2A | |
| SCHEMBL7458478 | 0.86 | KDM4E (0.76) | KDM4ESMN1; SMN2TP53RAB9AKMT2A | |
| SCHEMBL7459203 | 0.81 | KDM4E (0.68) | KDM4ESMN1; SMN2TP53KMT2ALMNA | |
| SCHEMBL3486583 | 0.79 | HSD11B1 (0.91) | KDM4EMAPTKMT2AHSD11B1LMNA | |
| SCHEMBL29506329 | 0.79 | HSD11B1 (0.91) | KDM4EMAPTKMT2AHSD11B1LMNA | |
| SCHEMBL14353530 | 0.78 | RAB9A (1.00) | SMN1; SMN2GBA1MAPTTP53RAB9A | |
| SCHEMBL6465229 | 0.77 | KDM4E (0.63) | KDM4ESMN1; SMN2TP53RAB9AKMT2A | |
| SCHEMBL6241750 | 0.77 | LMNA (0.80) | KDM4EMAPTTP53RAB9AKMT2A | |
| SCHEMBL6464247 | 0.77 | L3MBTL1 (0.72) | KDM4ESMN1; SMN2MAPTTP53RAB9A | |
| SCHEMBL5184740 | 0.77 | LMNA (0.69) | KDM4EMAPTTP53RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050255998-A1 | Mixture of colour developers | CIBA SPECIALTY CHEMICALS CORP. | 2005-11-17 | — | — | US | disclosed |
| US-20050106491-A1 | Heat sensitive recording material | CIBA SPECIALTY CHEMICALS CORP. | 2005-05-19 | — | — | US | disclosed |
| EP-1480835-A1 | HEAT SENSITIVE RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| EP-1480836-A1 | MIXTURE OF COLOUR DEVELOPERS | Ciba SC Holding AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074284-A1 | MIXTURE OF COLOUR DEVELOPERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003074285-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-12 | — | — | WO | disclosed |