Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.33 |
| ▸ | GART | P22102 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043199 | 0.91 | SCN9A (0.35) | CTSSPTPN1CTSLCTSKCYP3A4 | |
| SCHEMBL6464414 | 0.84 | FAAH (0.38) | CTSSGARTCYP3A4CYP2C9 | |
| SCHEMBL6468432 | 0.81 | GART (0.34) | CTSSGARTEPHX2CYP3A4CYP2C9 | |
| SCHEMBL6464521 | 0.81 | CTSS (0.38) | CTSSPTPN1CTSLCTSKEPHX2 | |
| SCHEMBL6465509 | 0.78 | LMNA (0.46) | CTSSCTSLEPHX2ADRB2ADRB1 | |
| SCHEMBL6062750 | 0.77 | EPHX2 (0.38) | CTSSGARTEPHX2CYP3A4CYP2C9 | |
| SCHEMBL7044860 | 0.77 | LMNA (0.44) | CTSSCTSLEPHX2ADRB2ADRB1 | |
| SCHEMBL6468407 | 0.76 | EPHX2 (0.38) | CTSSGARTEPHX2CYP3A4CYP2C9 | |
| SCHEMBL7049525 | 0.76 | GART (0.38) | CTSSGARTCYP3A4CYP2C9 | |
| SCHEMBL7043354 | 0.76 | EPHX2 (0.39) | CTSSGARTEPHX2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |