Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 9/20 | 0.34 |
| ▸ | XDH | P47989 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464414 | 0.90 | FAAH (0.38) | GARTFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL7045927 | 0.83 | CTSS (0.38) | ALDH1A1CTSSCYP3A4CYP2C9KDM4E | |
| SCHEMBL7048621 | 0.82 | CTSS (0.35) | ALDH1A1CTSSCYP3A4CYP2C9 | |
| SCHEMBL6465509 | 0.82 | LMNA (0.46) | ALDH1A1CTSSCYP3A4KDM4E | |
| SCHEMBL6466991 | 0.81 | CTSS (0.35) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6468432 | 0.81 | GART (0.34) | GARTALDH1A1CTSSCYP3A4CYP2C9 | |
| SCHEMBL6465159 | 0.80 | FAAH (0.44) | GARTFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL6464428 | 0.79 | CTSS (0.39) | FAAHCES1DAGLACTSSXDH | |
| SCHEMBL7044860 | 0.79 | LMNA (0.44) | CTSSCYP3A4CYP2C9KDM4EPOLB | |
| SCHEMBL7049143 | 0.78 | HTT (0.34) | CTSSCYP3A4CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | GART 2659/4885FAAH 479/4885CES1 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.