Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LONP1 | P36776 | 3/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465509 | 0.96 | LMNA (0.46) | LMNAHPGDHTTKDM4EEPHX2 | |
| SCHEMBL6464414 | 0.82 | FAAH (0.38) | CTSSCYP2C9CYP3A4 | |
| SCHEMBL7043354 | 0.80 | EPHX2 (0.39) | EPHX2CTSSCYP2C9CYP3A4 | |
| SCHEMBL7049525 | 0.79 | GART (0.38) | KDM4ECTSSPOLBCYP2C9CYP3A4 | |
| SCHEMBL6468432 | 0.78 | GART (0.34) | HPGDHTTKDM4EEPHX2CTSS | |
| SCHEMBL7048000 | 0.78 | POLB (0.36) | LMNAHPGDHTTKDM4EPOLB | |
| SCHEMBL6465945 | 0.77 | CTSS (0.33) | EPHX2CTSSADRB2ADRB1ADRB3 | |
| SCHEMBL6468407 | 0.76 | EPHX2 (0.38) | EPHX2CTSSPOLBCYP2C9CYP3A4 | |
| SCHEMBL7045927 | 0.76 | CTSS (0.38) | HTTKDM4EEPHX2CTSSCYP2C9 | |
| SCHEMBL7049143 | 0.76 | HTT (0.34) | HTTKDM4ECTSSCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | LMNA 1755/4885HPGD 536/4885HTT 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.