SCHEMBL6466087

SCHEMBL6466087

Cc1ccc(CS(=O)(=O)N(C(N)=O)c2ccc(Cc3ccc(N(C(N)=O)S(=O)(=O)Cc4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
POLB P06746 2/20 0.41
SRD5A2 P31213 1/20 0.40
RORC P51449 2/20 0.38
PTPN1 P18031 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.37
MMP2 P08253 2/20 0.37
MMP9 P14780 2/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6463099 0.87 HSP90AA1 (0.49) RORCPTPN1KDM4ELMNAALDH1A1
SCHEMBL6469558 0.85 KDM4E (0.40) KMT2AKDM4ELMNAALDH1A1TP53
SCHEMBL6466488 0.85 SAE1 (0.44) KMT2ALMNAALDH1A1KEAP1NFE2L2
SCHEMBL6462900 0.83 GRM2 (0.40) KMT2AKDM4ELMNAALDH1A1
SCHEMBL27679 0.82 LMNA (0.54) KMT2AKDM4ELMNAALDH1A1KEAP1
SCHEMBL20970044 0.80 SRD5A2 (0.44) KMT2ASRD5A2KDM4ELMNAALDH1A1
SCHEMBL8626825 0.79 ALDH1A1 (0.42) KMT2AKDM4ELMNAALDH1A1
SCHEMBL9435801 0.77 CNR2 (0.45) LMNAALDH1A1
SCHEMBL6464097 0.77 TDP1 (0.40) KMT2AKDM4EALDH1A1MAPT
SCHEMBL27521558 0.76 HSP90AA1 (0.59) RORCPTPN1KDM4EALDH1A1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed