Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | CPA2 | P48052 | 1/20 | 0.40 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.40 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.39 |
| ▸ | CTRL | P40313 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043370 | 0.90 | CA5A (0.51) | PSMB1 | |
| SCHEMBL6466256 | 0.89 | MMP9 (0.44) | MMP8PSMB1PSMB5PSMB2MMP3 | |
| SCHEMBL6467310 | 0.89 | MMP9 (0.44) | MMP8PSMB1PSMB5PSMB2MMP3 | |
| SCHEMBL6467305 | 0.89 | MMP9 (0.44) | MMP8PSMB1PSMB5PSMB2MMP3 | |
| SCHEMBL6467308 | 0.86 | CTSL (0.49) | PSMB1MMP3 | |
| SCHEMBL6062759 | 0.84 | PSMB1 (0.55) | PSMB1 | |
| SCHEMBL6466253 | 0.83 | TMPRSS11D (0.38) | ANPEPPSMB1PSMB5PSMB2MMP3 | |
| SCHEMBL6464784 | 0.82 | ANPEP (0.48) | ANPEPNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL6061832 | 0.82 | CTSL (0.52) | PSMB1MMP3MMP1 | |
| SCHEMBL6467335 | 0.82 | CTSL (0.51) | PSMB1MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |