Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.38 |
| ▸ | CTRL | P40313 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | CPA2 | P48052 | 1/20 | 0.36 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046085 | 0.91 | CTSL (0.47) | PSMB1CTSSCTSL | |
| SCHEMBL6464780 | 0.84 | CTSB (0.42) | TMPRSS11DCTRLPSMB5PSMB2PSMB1 | |
| SCHEMBL6466258 | 0.83 | ANPEP (0.46) | TMPRSS11DCTRLPSMB5PSMB2PSMB1 | |
| SCHEMBL6467305 | 0.83 | MMP9 (0.44) | TMPRSS11DCTRLRENPSMB5PSMB2 | |
| SCHEMBL6467310 | 0.83 | MMP9 (0.44) | TMPRSS11DCTRLRENPSMB5PSMB2 | |
| SCHEMBL6466256 | 0.83 | MMP9 (0.44) | TMPRSS11DCTRLRENPSMB5PSMB2 | |
| SCHEMBL6062791 | 0.78 | CTSL (0.54) | PSMB1CTSSCTSL | |
| SCHEMBL7046608 | 0.78 | CTSL (0.49) | PSMB1CTSSCTSL | |
| SCHEMBL6466880 | 0.78 | PSMB2 (0.45) | TMPRSS11DCTRLPSMB5PSMB2PSMB1 | |
| SCHEMBL6465769 | 0.76 | ALDH1A1 (0.39) | RENPSMB5PSMB2CTSSPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |