Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 9/20 | 0.41 |
| ▸ | MMP1 | P03956 | 8/20 | 0.41 |
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7114461 | 0.88 | CTSS (0.44) | FAAHCES1DAGLAMMP3MMP1 | |
| SCHEMBL6063084 | 0.86 | CTSS (0.53) | FAAHCES1DAGLAMMP3MMP1 | |
| SCHEMBL7047588 | 0.85 | FAAH (0.39) | FAAHCES1DAGLAMMP3MMP1 | |
| SCHEMBL7048552 | 0.85 | CTSS (0.39) | FAAHCES1DAGLAMMP3MMP1 | |
| SCHEMBL6467342 | 0.81 | DAGLA (0.41) | FAAHCES1DAGLAMMP3MMP1 | |
| SCHEMBL6464127 | 0.79 | CTSS (0.49) | MMP3MMP1MMP2CTSSCTSL | |
| SCHEMBL7049518 | 0.76 | DAGLA (0.46) | FAAHCES1DAGLA | |
| SCHEMBL6463072 | 0.74 | DAGLA (0.60) | FAAHCES1DAGLA | |
| SCHEMBL7049335 | 0.73 | DAGLA (0.42) | FAAHCES1DAGLAMMP2 | |
| SCHEMBL6461909 | 0.72 | EPHX2 (0.49) | FAAHCES1DAGLACTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | FAAH 479/4885CES1 272/4885DAGLA 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.