Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466348 | 0.81 | FAAH (0.43) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL6467344 | 0.77 | PRSS8 (0.45) | DAGLAFAAHCES1MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL7114461 | 0.77 | CTSS (0.44) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL6063084 | 0.77 | CTSS (0.53) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL7047588 | 0.76 | FAAH (0.39) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL7048552 | 0.76 | CTSS (0.39) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL6468626 | 0.76 | CTSS (0.44) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL6463414 | 0.76 | CTSS (0.44) | DAGLAFAAHCES1MMP1MMP2 | |
| SCHEMBL6463072 | 0.74 | DAGLA (0.60) | DAGLAFAAHCES1XDH | |
| SCHEMBL6467484 | 0.73 | DAGLA (0.39) | DAGLAFAAHCES1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |