Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 5/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456046 | 0.80 | CTSK (0.53) | CTSKCASP3CASP1CASP7 | |
| SCHEMBL6456049 | 0.80 | CTSK (0.53) | CTSKCASP3CASP1CASP7 | |
| SCHEMBL6466403 | 0.80 | SHMT2 (0.33) | CTSKSHMT2 | |
| SCHEMBL5096687 | 0.74 | CTSK (0.47) | CTSKCACNA1BLARS1 | |
| SCHEMBL5105564 | 0.74 | CTSK (0.47) | CTSKCACNA1BLARS1 | |
| SCHEMBL4689695 | 0.74 | ALDH1A1 (0.47) | CTSK | |
| SCHEMBL7425826 | 0.74 | ALDH1A1 (0.47) | CTSK | |
| SCHEMBL5096694 | 0.74 | CTSK (0.47) | CTSKCACNA1BLARS1 | |
| Hydrochloric Acid SCHEMBL6580442 | 0.73 | CTSK (0.66) | CTSK | |
| SCHEMBL7427967 | 0.73 | CACNA1B (0.53) | CACNA1BLARS1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203084-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203084-A1 | Protease inhibitors | SERPINB1, SPINT2, PRSS1 | CTSK 72/4885CACNA1B 3911/4885SHMT2 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.