SCHEMBL6466801

SCHEMBL6466801

Cc1ccc(S(=O)(=O)NC(=O)Nc2cc(C)on2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
GAA P10253 1/20 0.73
ALDH1A1 P00352 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
GBA1 P04062 1/20 0.62
KDM4E B2RXH2 1/20 0.60
PKM P14618 1/20 0.57
TSHR P16473 1/20 0.54
MAPT P10636 1/20 0.54
MAPK1 P28482 1/20 0.54
GAPDH P04406 1/20 0.53
TP53 P04637 1/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12879697 0.79 ALDH1A1 (0.77) LMNAALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL31026214 0.77 LMNA (0.62) LMNAGAAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL5184740 0.77 LMNA (0.69) LMNAGAAALDH1A1L3MBTL1RAB9A
SCHEMBL1928662 0.76 CA12 (0.85) LMNAALDH1A1L3MBTL1RAB9AKMT2A
SCHEMBL6243996 0.76 CA12 (0.85) LMNAALDH1A1L3MBTL1RAB9AKMT2A
SCHEMBL2632916 0.75 ALDH1A1 (0.63) LMNAGAAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL6465388 0.75 KDM4E (1.00) LMNAGAAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL8553736 0.75 LMNA (0.60) LMNAGAAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL8416917 0.75 LMNA (0.72) LMNAALDH1A1L3MBTL1RAB9AKMT2A
SCHEMBL6468156 0.75 ALDH1A1 (0.69) LMNAGAAALDH1A1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed