Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575216 | 1.00 | FAAH (0.36) | FAAHCES1DAGLACYP3A4XDH | |
| SCHEMBL7466136 | 0.94 | FAAH (0.36) | FAAHCES1DAGLACYP3A4XDH | |
| SCHEMBL6466197 | 0.94 | FAAH (0.36) | FAAHCES1DAGLACYP3A4XDH | |
| SCHEMBL7045360 | 0.89 | CYP3A4 (0.38) | CYP3A4XDHNPC1RAB9A | |
| SCHEMBL7049041 | 0.86 | ATM (0.38) | CYP3A4XDHNPC1RAB9A | |
| SCHEMBL6462134 | 0.84 | SMN1; SMN2 (0.34) | FAAHCES1DAGLACYP3A4XDH | |
| SCHEMBL6465390 | 0.83 | ALDH1A1 (0.41) | FAAHCES1DAGLATP53PTPN1 | |
| SCHEMBL6466278 | 0.82 | BMP1 (0.36) | LMNAPTPN1PTPN2NPC1RAB9A | |
| SCHEMBL6467558 | 0.80 | FAAH (0.46) | FAAHCES1DAGLACYP3A4XDH | |
| SCHEMBL6462287 | 0.80 | FAAH (0.44) | FAAHCES1DAGLACYP3A4XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |